To understand the molecular and physical factors that are involved in membrane protein assembly reactions in membranes, the laboratory applies theoretical approaches via computational modeling hand-in-hand with our experiments. The Robertson lab has expertise in many computational methods including homology modeling (Robertson et al. JGP 2008), continuum electrostatics calculations (Robertson et al. JGP 2008; Tan et al. 2009; Jayaram et al. Biochemistry 2011; Kawate et al. 2011), and molecular dynamics simulations (Robertson et al. BJ 2012).
This research has been supported by the supercomputer allocation grant PSCA17076P at the Pittsburgh Supercomputing Center.